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About UsChemistry

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Chemistry

Some of the chemistiy used on a daily base at Soneas R&D Laboratories, Pilot, cGMP Plant and Large Scale Manufacturing sites:

Acid chloride preparations
Alkylation (for example with diethyl sulfate)
Carbene additions
Carbonylation with CO
Cryogenic reactions (-70 °C ÷ -60 °C)
Cyanations
Cyclopentadiene chemistry
Cyclopropanation
Diazotation (for example Sandmeyer)
Diels Alder reactions
Friedel-Crafts reactions
Halogenations
  Bromination with Bromine
  Chlorination, by using chlorinating reagents (for example NCS)
  Fluorination, by using fluorinating reagents(for example DAST, XtalFluor)
High temperature reactions (150-250 °C)
Homogeneous catalytic coupling reactions
Hydrazine reaction
Hydrogenation
Hydroxyethylation/propylation with ethylene and propylene oxide
Isomerization
Metathesis reactions (with Mo, W, Ru catalyst)
Optical resolutions
Organo peroxide chemistry
Organometallic reagents (Grignard, Organolithium, Metal Hydrides)
Synthesis of boron organic compounds (for example organic boronic acids)
Triphosgene chemistry

LEGEND:

R&D Laboratories, Pilot, cGMP Plant and Large Scale Manufacturing sites
R&D Laboratories, Pilot
R&D Laboratories, cGMP Plant and Large Scale Manufacturing sites

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